Name: | TECA (Titrated Extract of Centella Asiatica) |
N° CAS: | 84696-21-9 |
N° CTFA: |
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N° EINECS: |
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Titration: | Asiaticoside 36%-44% |
Free genines (Asiatic acid & madecassic acid) 54%-66% |
TECA, also called Selected Centella Triterpenes, is a highly purified extract, fractioned and enriched in triterpenic acid and triterpenic sugar ester fractions to reach about 40% of asiaticoside and about 60% of the triterpenic genins (asiatic acid and madecassic acid).
The purification steps are extreme and involve chemical treatments that remove the herbal matrix so that the final extract is a recombination of a highly refined extract with an isolated constituent and the natural proportion of the components is not maintained.
TECA properties
TECA biological activities show to be efficient in 3 main domains
- Improve microcirculation mainly by reinforcing vessels’ walls. This characteristic permits also to reduce Oedema
- Promote dermis reconstruction by stimulating collagen I synthesis and protecting against matrix metalloproteinases (MMPs).
- Act on stretchmarks reduction and prevention
TECA applications
Medical use
- Venous Insufficiency [1, 2]
- Venous hypertensive angiopathy [3, 4]
- Airline flight microangiopathenous hypertensive angiopathy [5]
- Airline flight microangiopathy
Cosmetic application
- Dermis reconstruction
- Microcirculation activation
- Stretchmarks prevention & Treatment
- Anti-aging
- Skin repair
Recommended dosage : 0.5%
[1] Pointel JP, Boccalon H, Cloarec M, et al. Titrated extract of Centella asiatica (TECA) in the treatment of venous insufficiency of the lower limbs. Angiology 1987;38:46-50. LINK
[2] Cesarone MR, Laurora G, et al. [The microcirculatory activity of Centella asiatica in venous insufficiency. A double-blind study]. Minerva Cardioangiol 1994 Jun;42(6):299-304.
[3] Cesarone MR, Belcaro G, De Sanctis MT, et al. Effects of the total triterpenic fraction of Centella asiatica in venous hypertensive microangiopathy: a 67. Centella asiatica prospective, placebo-controlled, randomized trial. Angiology 2001;52:S15-S18. LINK
[4] Cesarone MR, Belcaro G, Rulo A, et al. Microcirculatory effects of total triterpenic fraction of Centella asiatica in chronic venous hypertension: measurement by laser Doppler, TcPO2-CO2, and leg volumetry. Angiology 2001;52:S45-S48. LINK
[5] Cesarone MR, Incandela L, De Sanctis MT, et al. Flight microangiopathy in medium- to long-distance flights: prevention of edema and microcirculation alterations with total triterpenic fraction of Centella asiatica. Angiology 2001;52:S33-S37. LINK
