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In-cosmetics 2013: biological activities of Centella’s Heterosides

Posted on 2 May 2013 in News

In-cosmetics 2013: biological activities of Centella’s Heterosides

This year 2013, at in-cosmetics, Bayer/Serdex has highlighted the biological activities of Heterosides of Centella Asiatica in relation with the H2O Trail. In the skin, H2O content (~75% in the dermis) diminishes during the keratinization process (basal layer of keratinocytes ~ 32%; horny layer ~13%). The prevention of cutaneous dryness is traditionally focused on moisturizing the epidermis and replenishing the essential nutrients it lacks.

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Centella asiatica protects against UVB

Posted on 18 Nov 2012 in News

Centella asiatica protects against UVB

A recent study, led at Korea Institute for Skin and Clinical Sciences in Seoul, has recently studied the protective effects of Centella Asiatica against ultraviolet B damages on skin. In details, this study aimed to evaluate the protective effects of Centella Asiatica against ultraviolet B (UVB) damage in human keratinocytes using microRNA (miRNA) expression profiling analysis. Titrated extract of Centella Asiatica (TECA) demonstrated low cytotoxicity in normal human HaCaT keratinocytes only at low doses (<5 µg/ml). While UVB (50 mJ/cm2) irradiation significantly decreased cell viability,...

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Genetic diversity of Centella asiatica in China analyzed

Posted on 16 Nov 2012 in News

Genetic diversity of Centella asiatica in China analyzed

Centella asiatica is considered to be an important plant species used in traditional Chinese medicine. To help the efficient use and conservation of this species, a recent research has investigated the genetic diversity of Centella Asiatica populations in China using inter-simple sequence repeat (ISSR) markers.14 natural populations (total of 162 individuals) has been used to estimate genetic diversity. The results of this study showed a relatively high genetic diversity at the species level. At the population level, the genetic diversity of Jinhua, Zhejiang Province and Jiujiang, Jiangxi...

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Centella asiatica Improves Behavioral Deficits in a Model of Alzheimer’s Disease

Posted on 3 Sep 2012 in News

Centella asiatica Improves Behavioral Deficits in a Model of Alzheimer’s Disease

Guided by the use of Centella Asiatica in Ayurvedic medecine to enhance memory and nerve function, a team of researchers from Portland, USA, led a research on the potential use of Centella Asiatica in fighting Alzheimer’s Disease. This research have come to the conclusion that Centella Asiatica offers a unique therapeutic mechanism and novel active compounds of potential relevance to the treatment of Alzheimer’s Disease.   In details, a water extract of Centella Asiatica (Gotu Kola Water) attenuated Aβ-associated behavioral abnormalities in the Tg2576 mouse, a murine...

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Antibiogram pattern of endophytic fungi isolated from Centella asiatica

Posted on 10 Aug 2012 in News

Antibiogram pattern of endophytic fungi isolated from Centella asiatica

In a recent research, an investigation has been led in an attempt to search for antibiogram pattern from an alternate natural source endophytic fungus. The study has revealed the presence of good antibacterial activity for the crude extracts of Penicillium sp. so. This means that this organism could be a good source for bioactive compounds and the isolated compounds can be further used as an antibacterial agents.[/box]   In details, the study was aimed to screen the antimicrobial potential of 6 endophytic fungi isolated from leaves of Centella asiatica plant. The endophytes were...

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